Panax ginseng and Panax quinquefolium are two important medicinal plants of Araliaceae. The traditional medicinal part (root) has been widely used for many years. A large number of studies have shown that chemical components of non-medicinal parts of Panax ginseng and Panax quinquefolium are similar to those of traditional medicinal parts, and have good biological functions. The comprehensive development and utilization of non-medicinal parts of  Panax ginseng and Panax quinquefolium are of great significance for the sustainable development of both industries, and the efficient utilization of the whole plant sets a a good example for the comprehensive development of other medicinal materials. Based on the research status of chemical composition, pharmacological activity and development and utilization of non-medicinal parts of Panax ginseng and Panax quinquefolium, combined with the research results of our research group′s work practice, this paper analyzes the development and utilization of non-medicinal parts of Panax ginseng and Panax quinquefolium, and puts forward the overall ideas and prospects for the development and utilization of non-medicinal parts of Panax ginseng and Panax quinquefolium, so as to provide some reference for the efficient utilization of Panax ginseng and Panax quinquefolium and the deep development of products.