Advances in Biocatalytic Transformation and Hypoglycemic Activity Research of Rare Ginsenosides
SUN Mei1，2，LI Jiwen1，2，MA Jinying2，LI Zhongyu2，LI Keke2，LU Mingming3，GONG Xiaojie1，2**
1. College of Biological Engineering， Dalian Polytechnic University， Dalian 116034， China；2. Col?
lege of Life Sciences， Dalian Minzu University， Dalian 116600， China；3. Dalian Fusheng Natural
Drug Development Co. ， Ltd， Dalian 116600， China
Abstract：Rare ginsenosides have shown promising therapeutic effects in the management of diabetes and its associated complications. This review provides an overview of the latest research progress in the biocatalytic transformation of rare ginsenosides. Furthermore, it summarizes their diverse roles in combating diabetes and its complications, including enhancing insulin sensitivity,preserving pancreatic islet β cells, promoting glucose uptake by peripheral tissues, and exerting antioxidative and anti-inflammatory effects. These findings serve as a valuable reference for the efficient conversion of rare ginsenosides and facilitate their application in the field of diabetes treatment.
